Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673734 | 0.93 | ADORA2A (0.51) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9670813 | 0.91 | ADORA2A (0.49) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9671653 | 0.91 | ADORA2A (0.49) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9671648 | 0.90 | ADORA2A (0.48) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9670797 | 0.89 | ADORA2A (0.42) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9671634 | 0.89 | ADORA2A (0.47) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9671639 | 0.89 | ADORA2A (0.41) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9671182 | 0.89 | SLC29A1 (0.41) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL9671626 | 0.88 | ADORA2A (0.46) | ADORA2AADORA2BADORA3ADORA1LMNA | |
| SCHEMBL965396 | 0.87 | ADORA2A (0.52) | ADORA2AADORA2BADORA3ADORA1SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102873-A | Viricides | SOUTHERN RESEARCH INSTITUTE (US) | 1992-04-07 | — | — | US | claimed |
| US-5102873-A | Viricides | SOUTHERN RESEARCH INSTITUTE (US) | 1992-04-07 | — | — | US | disclosed |