Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD1 | P21728 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670241 | 1.00 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9671564 | 1.00 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9671701 | 1.00 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9670343 | 0.98 | KCNH2 (0.65) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL9670538 | 0.91 | KCNH2 (0.72) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| Water SCHEMBL11573576 | 0.90 | KCNH2 (0.58) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL11619381 | 0.90 | KCNH2 (0.58) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11135530 | 0.90 | KCNH2 (0.57) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL12540145 | 0.90 | KCNH2 (0.83) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL21171856 | 0.90 | KCNH2 (0.83) | KCNH2CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093370-A | Useful prior to insertion of tracheotomy tube or discission | TOBISHI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1992-03-03 | — | — | US | disclosed |