Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943099 | 0.81 | USP2 (0.46) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL10655259 | 0.77 | USP2 (0.42) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL10788227 | 0.74 | USP2 (0.65) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL25872743 | 0.74 | TLR2 (0.60) | USP2HTTTLR2LPAR1LPAR3 | |
| SCHEMBL9516427 | 0.74 | LPAR1 (0.58) | USP2HTTPLA2G2CSPHK1PRKD3 | |
| SCHEMBL8595022 | 0.74 | USP2 (0.65) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL25872677 | 0.74 | TLR2 (0.60) | USP2HTTTLR2LPAR1LPAR3 | |
| SCHEMBL19264514 | 0.74 | TLR2 (0.60) | USP2HTTTLR2LPAR1LPAR3 | |
| SCHEMBL9127025 | 0.74 | USP2 (0.65) | USP2HTTMEN1THRBKMT2A | |
| SCHEMBL15267483 | 0.74 | TLR2 (0.60) | USP2HTTTLR2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321296-B1 | LIPID DERIVATIVES THEIR PREPARATION AND USE | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |