⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12147343 | 0.71 | — | — | |
| SCHEMBL19010106 | 0.65 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL19010102 | 0.65 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL9912001 | 0.63 | — | — | |
| SCHEMBL20465454 | 0.63 | — | — | |
| SCHEMBL2903732 | 0.62 | — | — | |
| SCHEMBL12147346 | 0.60 | PIK3CD (0.31) | — | |
| SCHEMBL12690040 | 0.60 | — | — | |
| SCHEMBL23861113 | 0.58 | — | — | |
| SCHEMBL12147347 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234045-B1 | A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | claimed |
| US-4843068-A | INSECTICIDES, MITICIDES, FUNGICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1989-06-27 | — | — | US | claimed |
| US-4739068-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1988-04-19 | — | — | US | claimed |
| US-4726836-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | claimed |
| EP-0234045-A2 | A pyrazole oxime derivative and its production and use | NIHON NOHYAKU CO., LTD. (JP) | 1987-09-02 | — | — | EP | claimed |
| EP-0085028-B1 | N-PHENYLSULFONYL-N'-PYRIMIDINYL AND TRIAZINYL UREAS | CIBA-GEIGY AG (CH) | 1987-03-25 | — | — | EP | claimed |
| US-4618363-A | N-phenylsulfonyl-N'-triazinylureas | CIBA-GEIGY CORPORATION (US) | 1986-10-21 | — | — | US | claimed |
| EP-0085028-A2 | N-Phenylsulfonyl-N'-pyrimidinyl and triazinyl ureas | CIBA-GEIGY AG (CH) | 1983-08-03 | — | — | EP | claimed |
| CN-109689645-A | Cyanoindole quinoline derivant as NIK inhibitor | 杨森制药有限公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-102421773-A | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 | BOEHRINGER INGELHEIM INT | 2012-04-18 | — | — | CN | disclosed |
| CN-102119160-A | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 | BOEHRINGER INGELHEIM INT | 2011-07-06 | — | — | CN | disclosed |
| CN-102089300-A | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 | VITAE PHARMACEUTICALS INC | 2011-06-08 | — | — | CN | disclosed |
| CN-102026985-A | Quinazoline derivatives as RAF kinase modulators and methods and uses thereof | AMBIT BIOSCIENCES CORPORATON | 2011-04-20 | — | — | CN | disclosed |
| EP-0234045-B1 | A PYRAZOLE OXIME DERIVATIVE AND ITS PRODUCTION AND USE | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4739068-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1988-04-19 | — | — | US | disclosed |
| US-4726836-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0085028-B1 | N-PHENYLSULFONYL-N'-PYRIMIDINYL AND TRIAZINYL UREAS | CIBA-GEIGY AG (CH) | 1987-03-25 | — | — | EP | disclosed |
| US-4648899-A | N-phenylsulfonyl-N'-triazinylureas | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| US-4618363-A | N-phenylsulfonyl-N'-triazinylureas | CIBA-GEIGY CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| EP-0085028-A2 | N-Phenylsulfonyl-N'-pyrimidinyl and triazinyl ureas | CIBA-GEIGY AG (CH) | 1983-08-03 | — | — | EP | disclosed |