Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 7/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675966 | 0.90 | KDM4E (0.46) | KMT2AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9675363 | 0.90 | KDM4E (0.47) | KMT2AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9674720 | 0.89 | KDM4E (0.39) | KMT2AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9673696 | 0.86 | PIM1 (0.48) | KMT2AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9675123 | 0.84 | PIM1 (0.56) | ALDH1A1HSD17B10HPGDKDM4EPIM1 | |
| SCHEMBL9791223 | 0.83 | KMT2A (0.47) | KMT2AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9675600 | 0.83 | KDM4E (0.54) | KMT2AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9674347 | 0.83 | PIM1 (0.44) | KMT2AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9673781 | 0.82 | PIM1 (0.43) | KMT2AALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL9791269 | 0.82 | KDM4E (0.45) | KMT2AALDH1A1HSD17B10HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011831-A | Bactericides | NIPPON SHINYAKU CO. LTD. (JP) | 1991-04-30 | — | — | US | claimed |
| EP-0315827-B1 | DERIVATIVES OF QUINOLINECARBOXYLIC ACID | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5011831-A | Bactericides | NIPPON SHINYAKU CO. LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| EP-0315827-A1 | Derivatives of quinolinecarboxylic acid | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1989-05-17 | — | — | EP | disclosed |