SCHEMBL9675359

SCHEMBL9675359

O=C(O)/C=C\C[C@H]1[C@@H](CO)[C@H]2CC[C@@H]1O2

nearest known ligand 0.43

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXA2R P21731 20/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10740044 1.00 TBXA2R (0.43) TBXA2R
SCHEMBL10649058 0.79 TBXA2R (0.40) TBXA2R
SCHEMBL10989889 0.79 TBXA2R (0.40) TBXA2R
SCHEMBL10649052 0.79 TBXA2R (0.40) TBXA2R
SCHEMBL10367422 0.79 TBXA2R (0.40) TBXA2R
SCHEMBL10986203 0.79 TBXA2R (0.40) TBXA2R
SCHEMBL10712181 0.79 TBXA2R (0.40) TBXA2R
SCHEMBL10730594 0.78 TBXA2R (0.60) TBXA2R
SCHEMBL9425514 0.78 TBXA2R (0.60) TBXA2R
SCHEMBL9718324 0.78 TBXA2R (0.60) TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232912-B1 HYDROXAMIC ACIDS OF 7-OXABICYCLOHEPTANE SUBSTITUTED ETHERS E.R. Squibb & Sons, Inc. (US) 1992-05-13 EP disclosed
EP-0232912-A1 Hydroxamic acids of 7-oxabicycloheptane substituted ethers E.R. Squibb & Sons, Inc. (US) 1987-08-19 EP disclosed
US-4654367-A ANTIALLERGY, ANTIINFLAMMATORY, ANTIPSORIATIC, PROSTAGLANDINS E. R. SQUIBB & SONS, INC. (US) 1987-03-31 US disclosed