Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | USP5 | P45974 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674221 | 0.78 | KMT2A (0.60) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| SCHEMBL990594 | 0.74 | MEN1 (0.60) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| SCHEMBL20665098 | 0.74 | MEN1 (0.60) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| SCHEMBL9257885 | 0.74 | MEN1 (0.55) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| SCHEMBL2146965 | 0.73 | MEN1 (0.68) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| SCHEMBL1027011 | 0.73 | HPGD (0.68) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| Hydrochloric Acid SCHEMBL9787788 | 0.72 | HPGD (0.66) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| Bromide SCHEMBL10432863 | 0.72 | HPGD (0.66) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| SCHEMBL4233005 | 0.72 | MEN1 (0.66) | MEN1HPGDKMT2AHSD17B10APAF1 | |
| SCHEMBL3083716 | 0.72 | KMT2A (0.53) | MEN1HPGDKMT2AHSD17B10APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |