Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | QPCT | Q16769 | 1/20 | 0.35 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.35 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675858 | 0.99 | CYP2B6 (0.36) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9677645 | 0.98 | CYP11B1 (0.36) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9677161 | 0.95 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9676897 | 0.87 | CYP11B1 (0.40) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9676938 | 0.86 | CYP2B6 (0.40) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9677154 | 0.85 | CYP11B1 (0.38) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9675582 | 0.84 | CYP19A1 (0.37) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9675282 | 0.84 | CYP2B6 (0.39) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9675514 | 0.83 | CYP2B6 (0.38) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 | |
| SCHEMBL9675800 | 0.83 | CYP11B1 (0.38) | CYP11B1CYP11B2CYP19A1TBXAS1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490703-A1 | Trisubstituted silylalkyl 1,2,4-triazole and imidazole phenyl borane derivatives | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| US-5091377-A | Trisubstituted silylalkyl 1,2,4-triazole and imidazole phenyl borane derivatives | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-02-25 | — | — | US | disclosed |