Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | DRD1 | P21728 | 1/20 | 0.67 |
| ▸ | DRD5 | P21918 | 1/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9676154 | 0.99 | CHRM2 (0.66) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL9676447 | 0.97 | CHRM2 (0.70) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9675216 | 0.95 | CHRM2 (0.62) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL10465480 | 0.94 | CHRM2 (0.61) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9676262 | 0.94 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9674061 | 0.92 | CHRM2 (0.56) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9676670 | 0.90 | CHRM2 (0.76) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL9675997 | 0.90 | CHRM2 (0.66) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL9674305 | 0.89 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL9674263 | 0.89 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306698-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THESE COMPOUNDS | Dr. Karl Thomae GmbH (DE) | 1992-03-25 | — | — | EP | disclosed |
| US-4931436-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0306698-A1 | Condensed diazepinones, processes for their preparation, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1989-03-15 | — | — | EP | disclosed |