Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752229 | 1.00 | PTPN11 (0.70) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL7330154 | 1.00 | PTPN11 (0.70) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL10749093 | 1.00 | PTPN11 (0.70) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL9330862 | 1.00 | PTPN11 (0.70) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL10748772 | 1.00 | PTPN11 (0.70) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL10751579 | 1.00 | PTPN11 (0.70) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL10748478 | 1.00 | PTPN11 (0.70) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL10751527 | 1.00 | PTPN11 (0.70) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL9723769 | 0.99 | PTPN11 (0.68) | PTPN11LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL10747218 | 0.98 | PTPN11 (0.67) | PTPN11LMNAMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091557-A | AMINO ACID DERIVATIVE HAVING LIQUID CRYSTAL PROPERTY AND PROCESS FOR PRODUCTION OF THE SAME | SHOWA DENKO K.K. (JP) | 1992-02-25 | — | — | US | disclosed |
| US-5041602-A | Cinnamic acid used as inexpensive starting material | SHOWA DENKO K.K. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0239444-A1 | Ferroelectric liquid crystal, process for its manufacture and its use in a liquid-crystal mixture | THOMSON-CSF (FR) | 1987-09-30 | — | — | EP | disclosed |