Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678690 | 1.00 | TDP1 (0.69) | TDP1KMT2AMEN1ATMACP3 | |
| SCHEMBL7565966 | 0.83 | TDP1 (0.74) | TDP1KMT2AMEN1ATMACP3 | |
| SCHEMBL30774302 | 0.83 | TDP1 (0.74) | TDP1KMT2AMEN1ATMACP3 | |
| SCHEMBL1200327 | 0.82 | TDP1 (0.71) | TDP1KMT2AMEN1ATMACP3 | |
| SCHEMBL27599033 | 0.82 | TDP1 (0.71) | TDP1KMT2AMEN1ATMACP3 | |
| SCHEMBL27710793 | 0.82 | TDP1 (1.00) | TDP1KMT2AMEN1ATMACP3 | |
| SCHEMBL35925 | 0.82 | TDP1 (1.00) | TDP1KMT2AMEN1ATMACP3 | |
| SCHEMBL29607554 | 0.82 | TDP1 (1.00) | TDP1KMT2AMEN1ATMACP3 | |
| SCHEMBL1386762 | 0.80 | TDP1 (0.69) | TDP1KMT2AMEN1ATMACP3 | |
| Ammonia Solution, Strong SCHEMBL21246668 | 0.80 | TDP1 (0.96) | TDP1KMT2AMEN1ATMACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316820-B1 | THIAZOLE COMPOUNDS, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |