SCHEMBL9679043

SCHEMBL9679043

C=C1NC(=O)N(CCC)C1=N

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9679072 0.74
SCHEMBL9679520 0.72
SCHEMBL11475404 0.68 SMN1; SMN2 (0.45) SMN1; SMN2
SCHEMBL9678054 0.67 KMT2A (0.54)
SCHEMBL10178353 0.67 SMN1; SMN2 (0.37) SMN1; SMN2
SCHEMBL13753310 0.66 F2 (0.42) SMN1; SMN2
SCHEMBL2728584 0.66 KMT2A (0.44) SMN1; SMN2
SCHEMBL13183831 0.65 SMN1; SMN2 (0.33) SMN1; SMN2
SCHEMBL13392622 0.64 SMN1; SMN2 (0.35) SMN1; SMN2
SCHEMBL10178055 0.64 SMN1; SMN2 (0.35) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4996219-A Antibody inhibitors BOEHRINGER MANNHEIM GMBH (DE) 1991-02-26 US claimed
EP-0373542-B1 IMIDAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Roche Diagnostics GmbH (DE) 1992-06-17 EP disclosed
US-4996219-A Antibody inhibitors BOEHRINGER MANNHEIM GMBH (DE) 1991-02-26 US disclosed
EP-0373542-A1 Imidazoline derivatives, process for their preparation and medicaments containing them Roche Diagnostics GmbH (DE) 1990-06-20 EP disclosed