Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 3/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680323 | 0.82 | CYP2C9 (0.40) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL9678848 | 0.82 | CYP2C9 (0.40) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL5739403 | 0.82 | CYP2C9 (0.40) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL28395791 | 0.82 | CYP2C9 (0.40) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL9738098 | 0.80 | EHMT2 (0.46) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL9737057 | 0.75 | CYP2C9 (0.46) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL30480079 | 0.75 | CYP2C9 (0.46) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL9737464 | 0.75 | CYP2C9 (0.46) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL24741355 | 0.75 | KMT2A (0.45) | CYP2C9CYP2C19EHMT2MEN1KMT2A | |
| SCHEMBL5739207 | 0.75 | KMT2A (0.45) | CYP2C9CYP2C19EHMT2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095118-A | PROCESS FOR THE PREPARATION OF D-(+)-BIOTIN | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0242686-B1 | PROCESS FOR THE PREPARATION OF D-(+)-BIOTINE | MERCK PATENT GmbH (DE) | 1992-01-29 | — | — | EP | disclosed |
| US-4937351-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-26 | — | — | US | disclosed |
| US-4877882-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-31 | — | — | US | disclosed |
| US-4837402-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-06-06 | — | — | US | disclosed |
| US-4732987-A | Process for the preparation of D-(+)-biotin | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-03-22 | — | — | US | disclosed |
| EP-0242686-A2 | Process for the preparation of D-(+)-biotine | MERCK PATENT GmbH (DE) | 1987-10-28 | — | — | EP | disclosed |