Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9680150

N.Nc1cccc(S(=O)(=O)O)c1N

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.62
GAA P10253 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CYP2C9 P11712 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
AURKA O14965 1/20 0.44
AURKB Q96GD4 1/20 0.44
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
HTR6 P50406 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32077 0.98 TTR (0.64) TTRGAACA12CA1CA2
SCHEMBL28165813 0.96 TTR (0.62) TTRGAACA12CA1CA2
SCHEMBL599747 0.86 TTR (0.59) TTRGAACA12CA1CA2
Ammonia Solution, Strong SCHEMBL3841757 0.82 GAA (0.62) TTRGAACA12CA1CA2
Ammonia Solution, Strong SCHEMBL3841754 0.82 GAA (0.62) TTRGAACA12CA1CA2
SCHEMBL2006103 0.80 TTR (0.64) TTRGAACA12CA1CA2
SCHEMBL9558885 0.80 TTR (0.64) TTRGAACA12CA1CA2
SCHEMBL30272576 0.79 GAA (0.65) TTRGAACA12CA1CA2
SCHEMBL29358062 0.79 GAA (0.65) TTRGAACA12CA1CA2
SCHEMBL90023 0.79 GAA (0.65) TTRGAACA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128455-A WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-07 US disclosed