Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997809 | 1.00 | EPHX2 (0.47) | EPHX2TAS1R3TAS1R1TAS1R2NTRK1 | |
| SCHEMBL29381250 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT | |
| SCHEMBL22787577 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT | |
| SCHEMBL5432481 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT | |
| SCHEMBL56008 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT | |
| SCHEMBL29502115 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT | |
| SCHEMBL57180 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT | |
| SCHEMBL57241 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT | |
| SCHEMBL29922190 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT | |
| SCHEMBL25730272 | 0.88 | MEN1 (0.52) | EPHX2KMT2AMEN1ALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106861-A | Method of using certain tetralin derivatives to produce analgesic relief | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5041673-A | Aminopeptidase inhibitors, immunomodulators, analgesics | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-08-20 | — | — | US | disclosed |