Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242062 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL18439038 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL7198242 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL9624268 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL9517492 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL8425793 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL12469797 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL6887082 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL9361594 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL10683838 | 0.92 | TSHR (0.77) | TSHRHPGDTHRBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463412-A1 | Magnetic colored encapsulated toner compositions | XEROX CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |
| US-5023159-A | Encapsulated electrophotographic toner compositions | XEROX CORPORATION (US) | 1991-06-11 | — | — | US | disclosed |