Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.55 |
| ▸ | CCR5 | P51681 | 3/20 | 0.55 |
| ▸ | CCR8 | P51685 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29654363 | 1.00 | CCR1 (0.55) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL16483065 | 0.86 | BRD4 (0.43) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL7918759 | 0.86 | POLB (0.67) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL24453801 | 0.84 | BRD4 (0.51) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL24475483 | 0.84 | BRD4 (0.51) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL17691832 | 0.83 | CCR1 (0.55) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL17334526 | 0.81 | CCR1 (0.62) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL29485612 | 0.81 | NPC1 (0.68) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL3726615 | 0.81 | NPC1 (0.68) | CCR1CCR5CCR8LMNAHTT | |
| SCHEMBL17345162 | 0.79 | CCR1 (0.50) | CCR1CCR5CCR8LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151478-A | Vapor phase polymerization of and condensation of polynuclear aromatic compounds and heterocyclic compounds | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1992-09-29 | — | — | US | disclosed |