Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952249 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL9462915 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL9463763 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL11463208 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL9370407 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL10839341 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL10952243 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL10368337 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL9463300 | 1.00 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL9425514 | 0.91 | TBXA2R (0.60) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093329-A | Intraocular pressure reducing prostaglandin-like 7-oxabicyclo derivatives | ALLERGAN, INC. (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0094792-B1 | 7-OXABICYCLOHEPTANE SUBSTITUTED AMINO PROSTAGLANDIN ANALOGS | E.R. Squibb & Sons, Inc. (US) | 1988-11-17 | — | — | EP | disclosed |
| EP-0079694-B1 | 7-OXABICYCLOPHEPTANE AND 7-OXABICYCLOHEPTENE COMPOUNDS | E.R. Squibb & Sons, Inc. (US) | 1987-05-13 | — | — | EP | disclosed |
| EP-0201811-A1 | 7-Oxabicycloheptane substituted aryl amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction | E.R. Squibb & Sons, Inc. (US) | 1986-11-20 | — | — | EP | disclosed |
| US-4614825-A | 7-oxabicycloheptane and 7-oxabicycloheptene compounds | E. R. SQUIBB & SONS, INC. (US) | 1986-09-30 | — | — | US | disclosed |
| US-4607048-A | 7-oxabicycloheptane substituted aryl amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| US-4582854-A | BRONCHODILATOR, ANTIINFLAMMATORY AGENT, ANALGESIC | E. R. SQUIBB & SONS, INC. (US) | 1986-04-15 | — | — | US | disclosed |
| US-4556675-A | 7-Oxabicycloheptane and 7-oxabicycloheptene compounds | E. R. SQUIBB & SONS, INC. (US) | 1985-12-03 | — | — | US | disclosed |
| US-4537981-A | 7-Oxabicycloheptane and 7-oxabicycloheptene compounds | E. R. SQUIBB & SONS, INC. (US) | 1985-08-27 | — | — | US | disclosed |
| US-4537904-A | Compositions of 7-oxabicycloheptane and 7-oxabicycloheptene compounds and a method for their use in inhibiting bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1985-08-27 | — | — | US | disclosed |
| US-4525479-A | 7-Oxabicycloheptane substituted thiocarbamate prostaglandin analogs useful as cardiovascular agents | E. R. SQUIBB & SONS, INC. (US) | 1985-06-25 | — | — | US | disclosed |
| US-4466979-A | 7-Oxabicycloheptane substituted carbamate prostaglandin analogs useful in treating platelet aggregation and bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4456617-A | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4456616-A | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4456615-A | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1984-06-26 | — | — | US | disclosed |
| EP-0107995-A1 | 7-Oxabicycloheptane substituted amino prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1984-05-09 | — | — | EP | disclosed |
| US-4418076-A | 7-Oxabicycloheptane hydrazone prostaglandin analogs useful in treating thrombolytic diseases | E. R. SQUIBB & SONS, INC. (US) | 1983-11-29 | — | — | US | disclosed |
| EP-0094792-A1 | 7-Oxabicycloheptane substituted amino prostaglandin analogs | E.R. Squibb & Sons, Inc. (US) | 1983-11-23 | — | — | EP | disclosed |
| US-4416896-A | 7-Oxabicyclopheptane substituted amino prostaglandin analogs useful in the treatment of thrombolytic disease | E. R. SQUIBB & SONS, INC. (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0079694-A1 | 7-Oxabicyclopheptane and 7-oxabicycloheptene compounds | E.R. Squibb & Sons, Inc. (US) | 1983-05-25 | — | — | EP | disclosed |