Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896226 | 0.93 | TSHR (0.39) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL8352195 | 0.78 | TSHR (0.39) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL15950043 | 0.78 | TSHR (0.44) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL2351408 | 0.78 | TSHR (0.39) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL11796169 | 0.75 | SMN1; SMN2 (0.39) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL7929601 | 0.75 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL5677899 | 0.75 | TSHR (0.50) | TSHRLMNAMEN1KMT2A | |
| SCHEMBL9778185 | 0.74 | SMN1; SMN2 (0.33) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| 1,4-Butanediol SCHEMBL18007026 | 0.74 | SMN1; SMN2 (0.53) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 | |
| SCHEMBL28283520 | 0.73 | TSHR (0.34) | TSHRSMN1; SMN2LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095044-A | Odorless, discoloration inhibition | CIBA-GEIGY CORPORATION (US) | 1992-03-10 | — | — | US | disclosed |
| US-4950795-A | PRINTING PLATES, PAPER COATING | CIBA-GEIGY CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |