Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.36 |
| ▸ | RELA | Q04206 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513812 | 1.00 | EPHX2 (0.46) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL10446423 | 0.88 | EPHX2 (0.45) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL9514046 | 0.83 | EPHX2 (0.47) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL9515086 | 0.81 | EPHX2 (0.46) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL9513939 | 0.81 | EPHX2 (0.46) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL9515288 | 0.81 | EPHX2 (0.46) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL9513879 | 0.81 | EPHX2 (0.46) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL3820432 | 0.79 | EPHX2 (0.46) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL7375062 | 0.78 | KDM1A (0.46) | EPHX2KDM1AMAOBDRD2KMT2A | |
| SCHEMBL7375058 | 0.78 | KDM1A (0.46) | EPHX2KDM1AMAOBDRD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106861-A | Method of using certain tetralin derivatives to produce analgesic relief | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-04-21 | — | — | US | disclosed |