Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830089 | 0.84 | POLB (0.41) | ATMNOTCH1POLBCCR2CTSK | |
| SCHEMBL10467154 | 0.77 | KMT2A (0.53) | ATMHPGDPOLBNOTUMKMT2A | |
| SCHEMBL9682508 | 0.77 | CYP2C19 (0.46) | NOTCH1KDM4EALDH1A1CYP2C9HPGD | |
| SCHEMBL3241127 | 0.76 | PLA2G10 (0.54) | ATMCYP2C9HPGDCYP2C19POLB | |
| SCHEMBL9299353 | 0.71 | HPGD (0.60) | KDM4EALDH1A1CYP2C9HPGDCYP2C19 | |
| SCHEMBL9832162 | 0.70 | CYP1A2 (0.43) | ALDH1A1CYP2C9CYP2C19POLBCCR2 | |
| SCHEMBL29985028 | 0.70 | CYP17A1 (0.45) | ALDH1A1HPGDCYP2C19CTSKNOTUM | |
| SCHEMBL403594 | 0.66 | POLB (0.56) | ALDH1A1HPGDCYP2C19POLBNOTUM | |
| SCHEMBL10842118 | 0.65 | KMT2A (0.51) | HPGDCYP2C19POLBCTSKNOTUM | |
| SCHEMBL18455052 | 0.64 | CYP2C9 (0.54) | KDM4EALDH1A1CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | claimed |
| US-5082949-A | Plant growth regulators, protective agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | disclosed |