Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 16/20 | 0.82 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.52 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681794 | 0.90 | TBXA2R (1.00) | TBXA2R | |
| SCHEMBL9683131 | 0.85 | TBXA2R (0.76) | TBXA2RDRD2NOD2GALR3NR2F2 | |
| SCHEMBL9681926 | 0.82 | TBXA2R (0.87) | TBXA2R | |
| SCHEMBL9681823 | 0.81 | TBXA2R (0.83) | TBXA2RMAPT | |
| SCHEMBL9683093 | 0.81 | TBXA2R (0.83) | TBXA2R | |
| SCHEMBL9683504 | 0.81 | TBXA2R (0.79) | TBXA2RDRD2MAPTNOD2 | |
| SCHEMBL9700305 | 0.80 | TBXA2R (0.82) | TBXA2RRAB9A | |
| SCHEMBL9683466 | 0.80 | TBXA2R (1.00) | TBXA2RRAB9A | |
| SCHEMBL9681366 | 0.80 | TBXA2R (0.67) | TBXA2RDRD2NOD1MAPTTNF | |
| SCHEMBL9683248 | 0.79 | TBXA2R (1.00) | TBXA2RDRD2NOD1MAPTNOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5021443-A | Noval benzimidazole and azabenzimiazole derivatives which are thromboxane receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present | LABORATOIRES UPSA (FR) | 1991-06-04 | — | — | US | disclosed |