Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 10/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722655 | 1.00 | LPAR3 (0.52) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL1233456 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL2691513 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL11670758 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL13478275 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL25323220 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL11672926 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL1235702 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL18964 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH | |
| SCHEMBL1230960 | 0.84 | LPAR3 (0.62) | LPAR3LPAR2TRPM8FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134236-A | Analgesics, antidepressants, anticonvulsants | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-07-28 | — | — | US | disclosed |
| US-4999356-A | Analgesics, antidepressants, anticonvulsants | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1991-03-12 | — | — | US | disclosed |
| EP-0302423-A2 | 1-Phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-02-08 | — | — | EP | disclosed |