Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079252 | 0.85 | GAA (0.58) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL2901212 | 0.85 | GAA (0.71) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL8771939 | 0.83 | GAA (0.59) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL8336245 | 0.82 | GAA (0.55) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL6234624 | 0.81 | GAA (0.58) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL28800695 | 0.81 | GAA (0.58) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL29494819 | 0.81 | GAA (0.58) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL1647940 | 0.81 | GAA (0.67) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL77511 | 0.80 | RECQL (0.55) | GAAKMT2AKDM4EHTTPOLB | |
| SCHEMBL4094277 | 0.80 | GAA (0.65) | GAAKMT2AKDM4EHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5124456-A | HINDERED AMINE-SUBSTITUTED DIHYDROPYRIDINES AND HEAT/LIGHT STABILIZATION OF POLYMER SUBSTRATES THEREWITH | RHONE-POULENC CHIMIE (FR) | 1992-06-23 | — | — | US | disclosed |