Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12353119 | 0.94 | MAOB (0.71) | SMN1; SMN2NPC1RAB9APOLBMAOB | |
| SCHEMBL23084938 | 0.94 | MAOB (0.71) | SMN1; SMN2NPC1RAB9APOLBMAOB | |
| SCHEMBL12353112 | 0.94 | MAOB (0.71) | SMN1; SMN2NPC1RAB9APOLBMAOB | |
| SCHEMBL25500912 | 0.94 | MAOB (0.71) | SMN1; SMN2NPC1RAB9APOLBMAOB | |
| SCHEMBL25503618 | 0.94 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1RAB9APOLBMAOB | |
| SCHEMBL25503616 | 0.94 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1RAB9APOLBMAOB | |
| SCHEMBL18821727 | 0.90 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9APOLBPARP10 | |
| SCHEMBL18821722 | 0.90 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9APOLBPARP10 | |
| SCHEMBL11911279 | 0.89 | MAOB (0.64) | SMN1; SMN2NPC1RAB9APOLBMAOB | |
| SCHEMBL23084944 | 0.87 | PARP10 (0.65) | SMN1; SMN2NPC1RAB9APOLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |
| EP-0354347-A2 | Liquid crystal compounds,their manufacture as modifiers for polycarbonates,polyestercarbonates and polyesters | BAYER AG (DE) | 1990-02-14 | — | — | EP | disclosed |