Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 17/20 | 1.00 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681351 | 1.00 | TBXA2R (1.00) | TBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL9681973 | 0.96 | TBXA2R (1.00) | TBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL9683272 | 0.95 | TBXA2R (1.00) | TBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL9682500 | 0.83 | TBXA2R (0.71) | TBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL9701513 | 0.78 | TBXA2R (0.68) | TBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL9681429 | 0.76 | TBXA2R (1.00) | TBXA2R | |
| SCHEMBL9682425 | 0.75 | TBXA2R (1.00) | TBXA2R | |
| SCHEMBL9699166 | 0.74 | TBXA2R (0.72) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9682881 | 0.73 | TBXA2R (0.69) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9581586 | 0.71 | TBXA2R (0.67) | TBXA2RAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | claimed |