Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72964 | 0.86 | CYP3A4 (0.49) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL9682091 | 0.79 | KMT2A (0.51) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL1713279 | 0.79 | KMT2A (0.75) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL2183176 | 0.79 | KMT2A (0.75) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL27885819 | 0.79 | KMT2A (0.75) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL1712998 | 0.79 | KMT2A (0.75) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL4748004 | 0.79 | KMT2A (0.75) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL1712995 | 0.79 | KMT2A (0.75) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL1713280 | 0.79 | KMT2A (0.75) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 | |
| SCHEMBL5460103 | 0.79 | KMT2A (0.75) | CYP2D6KMT2ACYP1A2HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |