SCHEMBL9682967

SCHEMBL9682967

Cc1ccc(C(=O)Oc2ccc(C(=O)Oc3ccc(O)cc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.61
ACR P10323 1/20 0.61
ALDH1A1 P00352 3/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
MAPT P10636 1/20 0.57
KMT2A Q03164 6/20 0.54
MEN1 O00255 2/20 0.54
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
LMNA P02545 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ESR1 P03372 1/20 0.53
ESR2 Q92731 1/20 0.53
ELANE P08246 1/20 0.51
CYP1A2 P05177 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223700 1.00 PRSS1 (0.61) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL16426421 1.00 PRSS1 (0.61) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL1129955 1.00 PRSS1 (0.61) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL13039037 0.95 PRSS1 (0.56) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL16372985 0.95 PRSS1 (0.56) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL19726963 0.95 PRSS1 (0.56) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL11111888 0.93 PARP10 (0.56) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL8929987 0.92 PRSS1 (0.69) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL9663961 0.92 PRSS1 (0.69) PRSS1ACRALDH1A1NPC1RAB9A
SCHEMBL2741098 0.92 PRSS1 (0.69) PRSS1ACRALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089590-A LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS BAYER AKTIENGESELLSCHAFT (DE) 1992-02-18 US disclosed
US-5084549-A Aromatic polyesters as thermoplastic molding materials BAYER AKTIENGESELLSCHAFT (DE) 1992-01-28 US disclosed
EP-0354347-A2 Liquid crystal compounds,their manufacture as modifiers for polycarbonates,polyestercarbonates and polyesters BAYER AG (DE) 1990-02-14 EP disclosed