SCHEMBL9682990

SCHEMBL9682990

O=C(O)Cc1ccc2ccccc2c1CC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.69
HSD17B10 Q99714 2/20 0.69
ALDH1A1 P00352 2/20 0.69
GAA P10253 2/20 0.69
GLA P06280 1/20 0.69
HPGD P15428 1/20 0.69
TDP1 Q9NUW8 1/20 0.65
AKR1B1 P15121 3/20 0.49
CYP1A2 P05177 3/20 0.45
CYP2C19 P33261 2/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.44
MAPT P10636 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
WDR5 P61964 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30238199 1.00 KDM4E (0.69) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL5802341 0.89 KDM4E (0.65) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL11460801 0.88 TDP1 (0.59) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL6577761 0.88 KDM4E (0.63) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL11766225 0.86 TDP1 (0.57) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL11497864 0.84 TDP1 (0.54) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL7798078 0.84 KDM4E (0.58) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL6753224 0.84 TDP1 (0.54) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL28003639 0.83 TDP1 (0.67) KDM4EHSD17B10ALDH1A1GAAGLA
SCHEMBL4889683 0.81 KDM4E (1.00) KDM4EHSD17B10ALDH1A1GAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5149486-A Vacuum forming liquid crystal polymer, improved elasticity for diaphragms MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-09-22 US disclosed
US-4880591-A BY MOLDING OF A MIXTURE OF LIQUID CRYSTAL POLYMERS AND FIBER OR FLAKE FILLER MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1989-11-14 US disclosed