Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685521 | 0.90 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1PNP | |
| SCHEMBL9857620 | 0.89 | HPRT1 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL9555558 | 0.83 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL9555553 | 0.83 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL9555585 | 0.83 | HSP90AA1 (0.34) | HSP90AA1HSP90AB1 | |
| SCHEMBL9675797 | 0.82 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1 | |
| SCHEMBL9675785 | 0.82 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1 | |
| SCHEMBL9186230 | 0.82 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1MAPK1CDK1CCNB1 | |
| SCHEMBL27462819 | 0.78 | HSP90AB1 (0.46) | HSP90AA1HSP90AB1CDK1CCNB1CCNE1 | |
| SCHEMBL9684337 | 0.77 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1PNPCDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |