Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | PPARG | P37231 | 2/20 | 0.79 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.79 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.79 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.79 |
| ▸ | ALB | P02768 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.77 |
| ▸ | APEX1 | P27695 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.77 |
| ▸ | RECQL | P46063 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11137369 | 0.94 | MAPT (0.79) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL11141891 | 0.94 | NR1I2 (0.74) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9683546 | 0.92 | NR1I2 (0.85) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9684883 | 0.92 | NR1I2 (0.88) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL11140729 | 0.91 | MAPT (0.70) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL11141835 | 0.91 | NR1I2 (0.72) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL11132951 | 0.91 | NR1I2 (0.72) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Hydrochloric Acid SCHEMBL9342790 | 0.91 | MAPT (0.85) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| Cefotaxime SCHEMBL27820833 | 0.90 | NR1I2 (0.94) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9683534 | 0.90 | NR1I2 (0.78) | NR1I2MAPTPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |