Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34295 | 0.98 | GAA (0.48) | GAAMAPTNOS2ALOX15HSD17B10 | |
| SCHEMBL29415525 | 0.98 | GAA (0.48) | GAAMAPTNOS2ALOX15HSD17B10 | |
| SCHEMBL29587280 | 0.95 | GAA (0.46) | GAAMAPTNOS2ALOX15HSD17B10 | |
| SCHEMBL28397446 | 0.95 | GAA (0.46) | GAAMAPTNOS2ALOX15HSD17B10 | |
| SCHEMBL28320372 | 0.95 | GAA (0.46) | GAAMAPTNOS2ALOX15HSD17B10 | |
| Potassium SCHEMBL9683518 | 0.95 | GAA (0.46) | GAAMAPTNOS2ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL9047476 | 0.95 | GAA (0.46) | GAAMAPTNOS2ALOX15HSD17B10 | |
| SCHEMBL8489461 | 0.95 | GAA (0.46) | GAAMAPTNOS2ALOX15HSD17B10 | |
| Bromide SCHEMBL8857359 | 0.95 | GAA (0.46) | GAAMAPTNOS2ALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL27563992 | 0.95 | GAA (0.46) | GAAMAPTNOS2ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1065865-A | Indoles and dihydroquinoline potassium channel openers | SQUIBB & SONS INC (US) | 1992-11-04 | — | — | CN | disclosed |
| CN-1065865-A | Indoles and dihydroquinoline potassium channel openers | SQUIBB & SONS INC (US) | 1992-11-04 | — | — | CN | disclosed |
| EP-0509762-A1 | Indole and dihydroquinoline potassium channel openers | E.R. SQUIBB & SONS, INC. (US) | 1992-10-21 | — | — | EP | disclosed |