Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19239219 | 0.98 | TSHR (0.56) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL9683695 | 0.84 | TSHR (0.57) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL18525833 | 0.83 | EPHX1 (0.61) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL14507335 | 0.83 | KDM4E (0.62) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL2771342 | 0.83 | RECQL (0.63) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL29004439 | 0.82 | TSHR (0.52) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL29004442 | 0.82 | TSHR (0.52) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL6014001 | 0.81 | EPHX1 (0.64) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL9002644 | 0.81 | EPHX1 (0.64) | TSHRLMNAEPHX2ALDH1A1RECQL | |
| SCHEMBL130413 | 0.81 | KDM4E (0.67) | TSHRLMNAEPHX2ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509795-A2 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-21 | — | — | EP | disclosed |
| US-5118678-A | Antibody inhibitors, antiinflammatory agents, fungicides, antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |