Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.71 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.68 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | DAO | P14920 | 1/20 | 0.67 |
| ▸ | SNCA | P37840 | 1/20 | 0.67 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | APEX1 | P27695 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684902 | 0.91 | NR1I2 (0.76) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL8651088 | 0.91 | NR1I2 (0.78) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL9683604 | 0.91 | NR1I2 (0.78) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL11491121 | 0.91 | NR1I2 (0.78) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL9683657 | 0.90 | NR1I2 (0.75) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL10627715 | 0.89 | NR1I2 (0.76) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL11157941 | 0.89 | NR1I2 (0.76) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL9659553 | 0.89 | NR1I2 (0.76) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL9659559 | 0.89 | NR1I2 (0.76) | NR1I2PGRHTR2CMAPTPPARG | |
| SCHEMBL10382883 | 0.89 | NR1I2 (0.70) | NR1I2PGRHTR2CMAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |