Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.55 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684940 | 0.89 | SMPD3 (0.70) | SMPD3NOX1MAPTTP53THRB | |
| SCHEMBL14301895 | 0.85 | SMPD3 (0.64) | SMPD3NOX1MAPTTP53THRB | |
| SCHEMBL12743187 | 0.84 | SMPD3 (0.59) | SMPD3NOX1MAPTTP53THRB | |
| SCHEMBL12824033 | 0.82 | SMPD3 (0.60) | SMPD3NOX1MAPTTP53THRB | |
| SCHEMBL15849234 | 0.81 | SMPD3 (0.59) | SMPD3NOX1MAPTTP53THRB | |
| SCHEMBL12928705 | 0.81 | NOX1 (0.45) | SMPD3NOX1MAPT | |
| SCHEMBL12106036 | 0.81 | SMPD3 (0.62) | SMPD3NOX1MAPTTP53THRB | |
| SCHEMBL12152262 | 0.81 | SMPD3 (0.59) | SMPD3NOX1MAPTTP53THRB | |
| SCHEMBL12152263 | 0.80 | SMPD3 (0.57) | SMPD3NOX1MAPTTP53THRB | |
| SCHEMBL12743185 | 0.80 | SMPD3 (0.54) | SMPD3NOX1MAPTTP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5164512-A | Triarylimidazole derivative, determination of hydrogen peroxide generated by enzymatic reaction | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0404526-A1 | Oxidizable color producing reagent | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-12-27 | — | — | EP | disclosed |