Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13601591 | 0.84 | PTPN7 (0.48) | ARTTRPTPRCKDM4ETDP1 | |
| SCHEMBL1899355 | 0.83 | POLB (0.53) | KDM4EALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL10787725 | 0.81 | TTR (0.58) | TTRPTPRCKDM4ETDP1ALDH1A1 | |
| SCHEMBL29370227 | 0.79 | KDM4E (0.55) | TTRPTPRCKDM4ETDP1POLB | |
| SCHEMBL7633476 | 0.79 | KDM4E (0.55) | TTRPTPRCKDM4ETDP1POLB | |
| SCHEMBL29699465 | 0.79 | KDM4E (0.55) | TTRPTPRCKDM4ETDP1POLB | |
| SCHEMBL629880 | 0.79 | MYC (0.54) | TTRPTPRCKDM4EALDH1A1POLB | |
| SCHEMBL10453980 | 0.78 | AR (0.49) | ARKDM4ETDP1ALDH1A1POLB | |
| SCHEMBL9435927 | 0.77 | PTPRC (0.56) | TTRPTPRCKDM4EALDH1A1POLB | |
| SCHEMBL890771 | 0.77 | AR (0.49) | ARKDM4EALDH1A1SRD5A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144028-A | Antibiotics | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0469844-A1 | 2-(9-fluorenonyl)-carbapenem | MERCK & CO. INC. (US) | 1992-02-05 | — | — | EP | disclosed |
| US-5025007-A | 2-(9-fluorenonyl)-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-06-18 | — | — | US | disclosed |