Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682816 | 0.95 | NPC1 (0.38) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL9479411 | 0.93 | KMT2A (0.43) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL9683301 | 0.88 | CA1 (0.40) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL9683305 | 0.88 | KMT2A (0.40) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL9682940 | 0.86 | MEN1 (0.38) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL9478676 | 0.83 | MAPT (0.37) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL9477385 | 0.82 | KMT2A (0.36) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL9587331 | 0.81 | KMT2A (0.43) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL9684536 | 0.81 | NPC1 (0.42) | NPC1GAAMEN1KMT2ACA1 | |
| SCHEMBL11035297 | 0.81 | EDNRA (0.42) | NPC1MAPTEDNRAPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499096-A1 | Substituted arylsulfonylaminoguanidinotriazines | BAYER AG (DE) | 1992-08-19 | — | — | EP | claimed |
| EP-0499096-A1 | Substituted arylsulfonylaminoguanidinotriazines | BAYER AG (DE) | 1992-08-19 | — | — | EP | disclosed |
| EP-0499096-A1 | Substituted arylsulfonylaminoguanidinotriazines | BAYER AG (DE) | 1992-08-19 | — | — | EP | disclosed |