Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 16/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | VCP | P55072 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PNP | P00491 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858327 | 0.88 | HPRT1 (0.58) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9185885 | 0.88 | BLM (0.61) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9184455 | 0.88 | BLM (0.61) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9182612 | 0.88 | BLM (0.61) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL10970953 | 0.88 | BLM (0.66) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9858092 | 0.85 | HPRT1 (0.66) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9537422 | 0.83 | MEN1 (0.78) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL8990372 | 0.83 | MEN1 (0.78) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL8990305 | 0.83 | MEN1 (0.78) | HPRT1MEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9684414 | 0.83 | HPRT1 (0.56) | HPRT1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |