Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 16/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685454 | 0.95 | GRM2 (0.41) | GRM2 | |
| SCHEMBL9743036 | 0.87 | GRM2 (0.36) | GRM2 | |
| SCHEMBL9744100 | 0.87 | GRM2 (0.36) | GRM2 | |
| SCHEMBL9743154 | 0.87 | GRM2 (0.36) | GRM2 | |
| SCHEMBL9323793 | 0.83 | GRM2 (0.58) | GRM2 | |
| SCHEMBL10252883 | 0.83 | GRM2 (0.44) | GRM2 | |
| SCHEMBL10249557 | 0.81 | GRM2 (0.42) | GRM2 | |
| SCHEMBL10249540 | 0.80 | GRM2 (0.40) | GRM2 | |
| SCHEMBL22771431 | 0.80 | — | — | |
| SCHEMBL22771439 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162322-A | Anxiolytic agetns; humans, animals | A. H. ROBBINS COMPANY, INCORPORATED (US) | 1992-11-10 | — | — | US | disclosed |
| US-5086055-A | Treating asthma, rhinitis, atopic dermatitis, chronic hives and conjunctivitis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-02-04 | — | — | US | disclosed |
| US-4886794-A | ANTIHISTAMINES, ANTIALLERGENS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-12-12 | — | — | US | disclosed |
| EP-0291244-A1 | Cyclic carbamate derivatives | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1988-11-17 | — | — | EP | disclosed |