⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21797549 | 0.59 | — | — | |
| SCHEMBL444735 | 0.54 | — | — | |
| SCHEMBL3678137 | 0.50 | ESR1 (0.42) | — | |
| SCHEMBL628054 | 0.45 | — | — | |
| SCHEMBL1650543 | 0.35 | — | — | |
| SCHEMBL741031 | 0.29 | — | — | |
| SCHEMBL4941989 | 0.29 | — | — | |
| SCHEMBL10534859 | 0.29 | — | — | |
| SCHEMBL2880835 | 0.29 | — | — | |
| SCHEMBL1187949 | 0.29 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111205310-A | Heterocyclic fused pyrimidine derivative, and pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2020-05-29 | — | — | CN | claimed |
| EP-0480204-A1 | Imidazole derivatives, potent and selective antagonists of angiotensin II receptor | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | claimed |
| CN-111205310-A | Heterocyclic fused pyrimidine derivative, and pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2020-05-29 | — | — | CN | disclosed |