Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.60 |
| ▸ | PGR | P06401 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.57 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | SNCA | P37840 | 1/20 | 0.57 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8649779 | 0.93 | NR1I2 (0.71) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL9682735 | 0.89 | NR1I2 (0.64) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL5972677 | 0.89 | NR1I2 (0.64) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL9682740 | 0.89 | NR1I2 (0.64) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL10422474 | 0.86 | MAPT (0.60) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11374304 | 0.86 | TDP1 (0.62) | NR1I2PGRTDP1MAPTCTDSP1 | |
| SCHEMBL11462677 | 0.85 | NR1I2 (0.74) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL11462676 | 0.85 | NR1I2 (0.74) | NR1I2PGRTDP1MAPTABCC4 | |
| SCHEMBL9684927 | 0.85 | NR1I2 (0.74) | NR1I2PGRTDP1MAPTABCC4 | |
| Hydrochloric Acid SCHEMBL11461005 | 0.84 | NR1I2 (0.73) | NR1I2PGRTDP1MAPTABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |