Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9462486 | 0.83 | ESR1 (0.61) | ALDH1A1CREBBPKDM4EESR1MAPT | |
| SCHEMBL9189659 | 0.83 | ESR1 (0.61) | ALDH1A1CREBBPKDM4EESR1MAPT | |
| SCHEMBL118684 | 0.81 | KDM4E (0.67) | ALDH1A1CREBBPKDM4EESR1NOS1 | |
| SCHEMBL29771053 | 0.81 | KDM4E (0.67) | ALDH1A1CREBBPKDM4EESR1NOS1 | |
| SCHEMBL28505227 | 0.79 | ESR1 (0.53) | ALDH1A1CREBBPKDM4EESR1MAPT | |
| SCHEMBL2546849 | 0.76 | CREBBP (0.69) | ALDH1A1CREBBPKDM4EESR1NOS1 | |
| SCHEMBL349741 | 0.76 | CREBBP (0.65) | ALDH1A1CREBBPKDM4EESR1NOS1 | |
| SCHEMBL6992124 | 0.76 | CREBBP (0.60) | ALDH1A1CREBBPKDM4EESR1NOS1 | |
| SCHEMBL13146791 | 0.76 | CREBBP (0.60) | ALDH1A1CREBBPKDM4EESR1NOS1 | |
| SCHEMBL6992123 | 0.76 | CREBBP (0.65) | ALDH1A1CREBBPKDM4EESR1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |