Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299228 | 0.87 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9300294 | 0.85 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9300535 | 0.84 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9300307 | 0.84 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DDUT | |
| SCHEMBL9299502 | 0.82 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DDUT | |
| SCHEMBL9299900 | 0.82 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9299713 | 0.80 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9299999 | 0.80 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9299993 | 0.79 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9300304 | 0.79 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518342-A1 | Chroman derivatives | Nippon Kayaku Kabushiki Kaisha (JP) | 1992-12-16 | — | — | EP | disclosed |