Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.64 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685355 | 1.00 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| SCHEMBL9684195 | 0.91 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| SCHEMBL9812077 | 0.91 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9683325 | 0.91 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| SCHEMBL9684201 | 0.91 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9683322 | 0.91 | ADRB3 (0.64) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| SCHEMBL9683356 | 0.88 | ADRB3 (0.58) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| SCHEMBL9683364 | 0.88 | ADRB3 (0.58) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| SCHEMBL7044330 | 0.86 | ADRB3 (0.71) | ADRB3ADRB1ADRB2MEN1ALDH1A1 | |
| SCHEMBL9684306 | 0.86 | ADRB3 (0.56) | ADRB3ADRB1ADRB2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |