Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 4/20 | 0.44 |
| ▸ | PPIF | P30405 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9687480 | 0.89 | KMT2A (0.55) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9686263 | 0.85 | KMT2A (0.48) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9687530 | 0.85 | KMT2A (0.48) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9686367 | 0.84 | NPC1 (0.57) | NPC1RAB9AKMT2AMEN1HTT | |
| SCHEMBL9686889 | 0.83 | KMT2A (0.51) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL3237870 | 0.82 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9686346 | 0.82 | KMT2A (0.52) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL9687229 | 0.81 | KMT2A (0.51) | NPC1RAB9AKMT2AMEN1LMNA | |
| Pyridine SCHEMBL10560765 | 0.80 | KMT2A (0.48) | NPC1RAB9AKMT2AMEN1LMNA | |
| SCHEMBL10561858 | 0.79 | KMT2A (0.58) | NPC1RAB9AKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268989-B1 | IMIDAZOPYRIDINE COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-07-08 | — | — | EP | disclosed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |