Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 11/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.55 |
| ▸ | PI4KA | P42356 | 3/20 | 0.53 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.53 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.53 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | THPO | P40225 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685043 | 0.88 | ADCY5 (0.47) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL9618444 | 0.87 | ADCY5 (0.60) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL21636982 | 0.81 | ADCY5 (0.66) | ADCY5ADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL10474172 | 0.80 | ADCY5 (0.74) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL24465167 | 0.79 | ADCY5 (0.64) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL20434928 | 0.79 | ADCY5 (0.64) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL9685235 | 0.79 | ADCY5 (0.64) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL20434932 | 0.79 | ADCY5 (0.64) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6045780 | 0.78 | ADCY5 (1.00) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6045752 | 0.78 | ADCY5 (1.00) | ADCY5ADORA2API4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468866-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | claimed |
| EP-0468866-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0468119-A1 | Novel carbocyclic analogs of certain nucleosides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |