Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ODC1 | P11926 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL988734 | 1.00 | TSHR (0.59) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL197255 | 1.00 | — | — | |
| Tetraethylene Glycol SCHEMBL6422627 | 0.97 | MEN1 (0.61) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL196866 | 0.97 | MEN1 (0.61) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL30230201 | 0.97 | MEN1 (0.61) | TSHRMAPK1MEN1KMT2ATHRB | |
| Triethylene Glycol SCHEMBL5269020 | 0.97 | MEN1 (0.61) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL560724 | 0.97 | MEN1 (0.61) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL3284317 | 0.97 | TSHR (0.56) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL4761582 | 0.92 | — | — | |
| Ethylene Glycol SCHEMBL1160257 | 0.91 | ODC1 (0.45) | TSHRMAPK1MEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079155-A | Bioaffinity chromatography | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-07 | — | — | US | disclosed |