SCHEMBL9686290

SCHEMBL9686290

O=C(O)c1c(Br)c(Br)c(Br)c(Br)c1C(=O)O.[KH]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.43
PRSS1 P07477 3/20 0.43
PRSS2 P07478 3/20 0.43
PRSS3 P35030 3/20 0.43
CYP1A2 P05177 1/20 0.43
PTPN1 P18031 1/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
ALOX15 P16050 2/20 0.34
HIF1A Q16665 2/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX12 P18054 1/20 0.34
CASP1 P29466 1/20 0.34
BRCA1 P38398 1/20 0.34
STAT6 P42226 1/20 0.34
CASP7 P55210 1/20 0.34
HBB P68871 1/20 0.34
CA1 P00915 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28626737 1.00 F2 (0.43) F2PRSS1PRSS2PRSS3CYP1A2
SCHEMBL35828 0.97 CYP1A2 (0.45) F2PRSS1PRSS2PRSS3CYP1A2
SCHEMBL29514787 0.97 CYP1A2 (0.45) F2PRSS1PRSS2PRSS3CYP1A2
SCHEMBL11014460 0.93 F2 (0.43) F2PRSS1PRSS2PRSS3CYP1A2
SCHEMBL17799765 0.93 F2 (0.43) F2PRSS1PRSS2PRSS3CYP1A2
SCHEMBL5704041 0.93 F2 (0.43) F2PRSS1PRSS2PRSS3CYP1A2
Ammonia Solution, Strong SCHEMBL11581671 0.93 F2 (0.43) F2PRSS1PRSS2PRSS3CYP1A2
Hydrochloric Acid SCHEMBL10627844 0.93 F2 (0.43) F2PRSS1PRSS2PRSS3CYP1A2
Ammonia Solution, Strong SCHEMBL11581673 0.93 F2 (0.43) F2PRSS1PRSS2PRSS3CYP1A2
SCHEMBL11016206 0.93 F2 (0.43) F2PRSS1PRSS2PRSS3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4277379-A AQUEOUS PASTE OF MONOBASIC TETRACHLORO OR TETRABROMOPHTHALATE SALT APEX CHEMICAL COMPANY, INC. (US) 1981-07-07 US claimed
US-5114786-A TETRABROMOPHTHALIC ACID SALT, MAGNESIUM SULFATE APEX CHEMICAL CORP. (US) 1992-05-19 US disclosed
US-4277379-A AQUEOUS PASTE OF MONOBASIC TETRACHLORO OR TETRABROMOPHTHALATE SALT APEX CHEMICAL COMPANY, INC. (US) 1981-07-07 US disclosed