⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentane SCHEMBL11737194 | 0.96 | TSHR (0.58) | — | |
| Hexane SCHEMBL4325387 | 0.91 | TSHR (0.58) | — | |
| Hexane SCHEMBL9244722 | 0.91 | TSHR (0.58) | — | |
| Hexane SCHEMBL9879436 | 0.91 | TSHR (0.58) | — | |
| Hexane SCHEMBL4330650 | 0.91 | TSHR (0.58) | — | |
| Hexane SCHEMBL4333874 | 0.91 | TSHR (0.58) | — | |
| Hexane SCHEMBL3782949 | 0.91 | TSHR (0.58) | — | |
| Hexane SCHEMBL55152 | 0.91 | TSHR (0.58) | — | |
| Pentane SCHEMBL9002883 | 0.91 | — | — | |
| Benzene SCHEMBL11638876 | 0.89 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230110495-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2023-04-13 | — | — | US | disclosed |
| CN-114980886-A | Compounds and methods for treating oxalate-related diseases | 奥沙鲁克斯公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11389456-B2 | Compounds and methods for treating oxalate-related diseases | OXALURX, INC. (US) | 2022-07-19 | — | — | US | disclosed |
| EP-4017490-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | Oxalurx, Inc. (US) | 2022-06-29 | — | — | EP | disclosed |
| WO-2021035196-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2021-02-25 | — | — | WO | disclosed |
| US-20210052586-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2021-02-25 | — | — | US | disclosed |
| US-20200390778-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. | 2020-12-17 | — | — | US | disclosed |
| WO-2019165159-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2019-08-29 | — | — | WO | disclosed |
| EP-2176654-B1 | BIOSENSOR | UNIV LEEDS INNOVATIONS LTD (GB) | 2017-03-22 | — | — | EP | disclosed |
| US-20160377571-A1 | BIOSENSOR | UNIVERSITY OF LEEDS (GB) | 2016-12-29 | — | — | US | disclosed |
| US-4427685-A | ANTIHISTAMINES, ANTIINFALMMATORY AGENTS | BEECHAM GROUP P.L.C. (GB) | 1984-01-24 | — | — | US | disclosed |
| US-4407823-A | ANTIINFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| EP-0089153-A2 | Pyridine derivatives | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-09-21 | — | — | EP | disclosed |
| US-4396626-A | (1-METHYL-4-TRIFLUOROMETHYL-5-ARYLCARBONYL-4-PYRRYL)ALKANOIC ACID OR DERIVATIVE; ANALGESIC, ANTIINFLAMMATORY | BEECHAM GROUP LIMITED (GB) | 1983-08-02 | — | — | US | disclosed |
| US-4376121-A | Antiallerigically-active imidazothienopyrimidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1983-03-08 | — | — | US | disclosed |
| US-4182891-A | ENZYME INHIBITORS, IMMUNOSUPPRESSANTS, CONTROL OF NEOPLASTIC GROWTH | MERRELL TORAUDE ET COMPAGNIE (FR) | 1980-01-08 | — | — | US | disclosed |
| US-4073936-A | Hypolipidemic allene carboxylic esters | SANDOZ, INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4036840-A | ENZYME INHIBITORS | ICN PHARMACEUTICALS (US) | 1977-07-19 | — | — | US | disclosed |
| US-3998808-A | INSECTICIDES, FUNGICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |
| US-3940441-A | BACTERICIDE | STERLING DRUG INC. (US) | 1976-02-24 | — | — | US | disclosed |