⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9644761 | 0.79 | — | — | |
| SCHEMBL11107319 | 0.79 | — | — | |
| SCHEMBL1306918 | 0.76 | — | — | |
| SCHEMBL31283823 | 0.70 | — | — | |
| SCHEMBL9572667 | 0.70 | — | — | |
| SCHEMBL900344 | 0.70 | — | — | |
| SCHEMBL1544669 | 0.70 | — | — | |
| SCHEMBL7318342 | 0.70 | — | — | |
| SCHEMBL1095879 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL8785894 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353102-B2 | Non-annulated thiophenylamides | HOFFMANN-LA ROCHE INC. (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2895481-A1 | NON-ANNULATED THIOPHENYLAMIDES AS INHIBITORS OF FATTY ACID BINDING PROTEINI(FABP) 4 AND/OR 5 | F. Hoffmann-La Roche AG (CH) | 2015-07-22 | — | — | EP | disclosed |
| US-20150183778-A1 | New non-annulated thiophenylamides | HOFFMANN-LA ROCHE INC. (US) | 2015-07-02 | — | — | US | disclosed |
| WO-2014040938-A1 | NON-ANNULATED THIOPHENYLAMIDES AS INHIBITORS OF FATTY ACID BINDING PROTEINI(FABP) 4 AND/OR 5 | F. HOFFMANN-LA ROCHE AG (CH) | 2014-03-20 | — | — | WO | disclosed |
| EP-0274009-B1 | OXADIAZOLYLACETONITRILES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-09-09 | — | — | EP | disclosed |
| EP-0274009-A1 | Oxadiazolylacetonitriles, their preparation and use | NOVO NORDISK A/S (DK) | 1988-07-13 | — | — | EP | disclosed |